Scientist - Peptide Process R &D
7 hours ago
About the jobJob DescriptionJob Title: Scientist - Peptide Process R &D ( Proven track record in both SPPS and LPPS is highly desirable) Education & Experience : M.Sc./PhD Organic chemistry with experience on Peptide Process R &D with 3 to 15 years of experience. . 1.0 Position SummaryWe are seeking a highly skilled and motivated Research Scientist specializing in peptide chemistry. The ideal candidate will be responsible for the design, execution, optimization, and scale-up of synthetic peptides using both Solid-Phase Peptide Synthesis (SPPS) and Liquid-Phase Peptide Synthesis (LPPS) methodologies. This role requires hands-on expertise in various synthesis techniques, purification, and analytical characterization, as well as a strong commitment to safety, documentation, and project management within a dynamic R&D environment.2.0 Key ResponsibilitiesA. Peptide Synthesis & DevelopmentDesign and execute multi-step synthesis of complex peptides (up to 30-40 mers) using manual and automated SPPS techniques.Demonstrate expertise with a wide range of peptide synthesis resins (e.g., 2-CTC, Rink Amide, Wang, Sieber) and select appropriate resins, protecting groups (Fmoc/Boc), coupling reagents, and solvents for target sequences.Perform advanced peptide modifications, including disulfide bridging, lactamization, and other cyclization strategies.Conduct peptide synthesis in solution phase (LPPS) utilizing both Fmoc and Boc protection strategies.Expertly carry out critical downstream processes, including resin cleavage, global deprotection, quenching, and product isolation.B. Instrumentation & TechnologyOperate, troubleshoot, and maintain automated peptide synthesizers.Utilize microwave peptide synthesizers (e.g., CEM Liberty Blue) to optimize reaction conditions and improve synthesis efficiency.Conduct synthesis at various scales using manual peptide reactors (1 L to 10 L).C. Purification & AnalysisPurify crude peptides using preparative Reverse-Phase High-Performance Liquid Chromatography (RP−HPLC) and perform subsequent lyophilization.Interpret analytical data (e.g., HPLC, Mass Spectrometry) to assess reaction progress, purity, and yield, and generate trend data to guide process optimization.Conduct comprehensive literature surveys to support the development of novel and efficient synthesis strategies.D. Compliance, Safety & DocumentationMaintain meticulous, real-time documentation of all experiments and results in an Electronic Lab Notebook (eLN).Ensure strict adherence to laboratory safety procedures to prevent incidents and maintain a safe working environment.Provide technical support for the technology transfer and execution of peptide manufacturing in GMP plant environments.Ensure timely calibration and proper functioning of laboratory instruments, including analytical balances and pH meters.E. Project Management & CollaborationEffectively plan and execute projects to ensure timely completion and achievement of R&D milestones.Engage in regular interaction and coordination with the Cross-Functional Team (CFT), including Analytical, Quality, and Manufacturing departments.
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Scientist - Peptide Process R &D
7 hours ago
Hyderabad, India Aurigene Pharmaceutical Services Limited Full timeAbout the job Job Description Job Title: Scientist - Peptide Process R &D ( Proven track record in both SPPS and LPPS is highly desirable) Education & Experience : M.Sc./PhD Organic chemistry with experience on Peptide Process R &D with 3 to 15 years of experience. . 1.0 Position Summary We are seeking a highly skilled and motivated Research Scientist...
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Scientist - Peptide Process R &D
2 hours ago
hyderabad, India Aurigene Pharmaceutical Services Limited Full timeAbout the jobJob DescriptionJob Title: Scientist - Peptide Process R &D ( Proven track record in both SPPS and LPPS is highly desirable) Education & Experience : M.Sc./PhD Organic chemistry with experience on Peptide Process R &D with 3 to 15 years of experience. . 1.0 Position SummaryWe are seeking a highly skilled and motivated Research Scientist...
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Scientist - Peptide Process R &D
3 hours ago
Hyderabad, India Aurigene Pharmaceutical Services Limited Full timeAbout the jobJob DescriptionJob Title: Scientist - Peptide Process R &D ( Proven track record in both SPPS and LPPS is highly desirable) Education & Experience : M.Sc./PhD Organic chemistry with experience on Peptide Process R &D with 3 to 15 years of experience. . 1.0 Position SummaryWe are seeking a highly skilled and motivated Research Scientist...
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Scientist - Analytical R&D
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Hyderabad, India Aurigene Pharmaceutical Services Limited Full timeJob Description We are Expanding our Biologics R&D Teams! If you're looking for a new opportunity or know someone who is, don't miss this chance to be part of an innovative team. Apply and enroll for our recruitment drive to meet our team, explore exciting career prospects, and take the next step in your career journey with us! Qualifications: Masters in any...
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Hyderabad, Telangana, India MSN Group Full time ₹ 9,00,000 - ₹ 12,00,000 per yearWe have requirement for R&D Peptide Downstream Purification.We are looking for 3 to 6 Years of Experience in Downstream purification. Having CDMO Division exp, is added advantage.Work Location: CRAMSN Research Park, Pashmylaram, Patancheru, Hyderabad.
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Scientist II
1 week ago
Hyderabad, Telangana, India HETERO LABS LIMITED Full time ₹ 12,00,000 - ₹ 36,00,000 per yearCompany overview:Hetero Drugs is an Indian pharmaceutical company and the world's largest producer of anti-retroviral drugs. Hetero's business includes APIs, generics, biosimilars, custom pharmaceutical services, and branded generics.Job Title: Scientist II - Formulation Research and Development (Injectables)Department: Formulation R&D (FR&D)Location:...
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Hyderabad, Telangana, India Morepen Laboratories Full time ₹ 12,00,000 - ₹ 36,00,000 per yearAbout UsMorepen Proprietary Drug Research Pvt Ltd. (MPDRPL) is a leading small-molecule CRDMO providing end-to-end Integrated API Development and Manufacturing solutions to global pharmaceutical and biotech industries. We specialize in APIs, intermediates, and KSMs, combining innovation, scalability, and sustainability.Position OverviewWe are seeking a...
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Analytical R&d
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Hyderabad, India Cellix Bio Full timeHere, everyone matters and you will be a vital contributor to our inspiring, bold mission. You will help make an impact on people’s lives and change futures every day. We are equally committed to bringing out your best and fostering a collaborative workplace built on trust and respect. We empower our people to take charge of their potential. We offer...
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Peptide Chemist
5 days ago
Hyderabad, Telangana, India Sai Life Full time**Responsibilities**: - Plan and execute synthesis of peptides (Solid and Solution phase) as per the requirements of the project - Adhere to EHS/SHE, Data Integrity and IPM compliance - Sound presentation and communication skills **Requirements**: - Practical knowledge in synthesis of peptides through solid and solution phase. Understand the significance...
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Formulation R&d Scientist
1 week ago
Hyderabad, India Cellix Bio Full timeHere, everyone matters and you will be a vital contributor to our inspiring, bold mission. You will help make an impact on people’s lives and change futures every day. We are equally committed to bringing out your best and fostering a collaborative workplace built on trust and respect. We empower our people to take charge of their potential. We offer...
