Pharmaceutical Specialist
1 day ago
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About the Company
The Catalyst Development & Scale-Up In charge will lead the research, development, optimization, and scale-up of catalyst systems used in pharmaceutical manufacturing processes. This role bridges laboratory innovation with plant-level implementation, ensuring efficient, cost-effective, and compliant production of high-quality intermediates and APIs. The position requires strong expertise in catalysis chemistry, process knowledge, scale-up methodologies and precious metal inventory management.
About the Role
The Catalyst Development & Scale-Up In charge will lead the research, development, optimization, and scale-up of catalyst systems used in pharmaceutical manufacturing processes.
Responsibilities
Catalyst Research & Development
- Design, synthesize, and optimize heterogeneous and/or homogeneous catalysts for pharmaceutical reactions. Particularly, Pd, Pt, Ru, Rh on supports like activated carbon, alumina and other supports.
- Very good fundamental understanding on catalysis, particularly pharma catalysts and good organic chemistry to understand the reaction mechanisms.
- Conduct lab-scale experiments to evaluate catalyst activity, selectivity, stability, and recyclability.
- Perform mechanistic studies to understand reaction pathways and catalyst behavior.
- Screen novel catalytic systems for yield improvement, loss of precious metal, process efficiency, and sustainability.
Process Scale-Up
- Translate lab-scale catalytic processes into pilot and commercial-scale operations.
- Develop scale-up protocols considering heat/mass transfer, reactor design, and safety requirements.
- Optimize reaction conditions for throughput, cost reduction, and waste minimization.
- Collaborate with process engineers to modify and adapt equipment for scale-up.
Technical Documentation & Compliance
- Prepare process development reports, scale-up protocols, and technical transfer documents.
- Ensure compliance with GMP, safety, and environmental regulations.
- Maintain detailed experimental records and batch manufacturing instructions.
- Support regulatory filings by providing technical data and process descriptions.
Cross-Functional Collaboration
- Work closely with R&D chemists, analytical teams, production, and quality control.
- Liaise with procurement and vendors for catalyst raw materials and equipment.
- Provide technical training to production teams on catalyst handling and process parameters.
Qualifications
- Master’s or Ph.D. in Chemistry, Chemical Engineering, or related field, with specialization in catalysis or process chemistry.
- 7+ years of experience in catalyst development, preferably in a pharmaceutical or fine chemical manufacturing environment.
- Proven track record of taking catalytic processes from lab concept to commercial scale.
- Strong understanding of chemical kinetics, reactor design, and process safety.
- Familiarity with GMP, ICH guidelines, and regulatory requirements for pharmaceutical manufacturing.
Required Skills
- Deep knowledge of homogeneous/heterogeneous catalysis, metal complexes, and enzyme catalysis.
- Strong problem-solving skills for troubleshooting process deviations.
- Proficiency in analytical techniques (GC, HPLC, ICP-MS, XRD, BET surface analysis, etc.).
- Ability to lead cross-functional technical teams.
- Excellent technical writing and presentation skills.
Preferred Skills
- Experience in a lab and pilot plant environment with periodic visits to production facilities.
- Exposure to chemicals and equipment; adherence to strict safety protocols required.
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