Senior Research Associate
3 weeks ago
Designation: Senior Research Associate – ADME BA
Department: Syngene Amgen R&D Center (SARC) - DMPK
Job Location: Bangalore
About Syngene:
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit.
Mandatory expectation for all roles as per Syngene safety guidelines:
Overall adherence to safe practices and procedures of oneself and the teams aligned Contributing to development of procedures, practices and systems that ensures safe operations and compliance to companys integrity & quality standards Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times. Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace. Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self Compliance to Syngene s quality standards at all times.Job Purpose:
A highly motivated individual with strong interest in in vivo/ in vitro bioanalysis is required for SARC (Syngene Amgen Research center) collaboration. In this position, candidate will perform compound screening to support drug discovery.
Key Responsibilities:
Well versed with processing techniques like LLE, SPE and protein precipitation. Carryout sample processing from biological matrices including but not limited to plasma, serum, blood etc for bioanalysis. Adequate troubleshooting knowledge is required. Conduct in vitro assays (Microsomal Stability, Plasma Protein binding, CYP inhibition etc.) Develop adequate LC-MS/MS methods for Bioanalysis to support drug discovery assays. Able to trouble shoot chromatography issue during method development and sample analysis. WATSON and WinNonlin handling is an added advantage. Support routine LC-MS/MS maintenance by coordinating with internal / external stakeholders. Attention to detail and effective communication and documentation skills is desired. Adherence to Good Research practices of the organization.Educational Qualification: M. Pharm from reputed university /MSc (Chemistry/ Analytical chemistry).
Work Experience: 3-6 years in industry.
Technical/Functional Skills:
Proficiency in LC-MS/MS bioanalysis and aware of basic instrument maintenance. Should conduct bioanalysis of In-vivo (PK/TK)/In-vitro ADME samples using LC-MS/MS.Behavioral/Managerial Skills:
Good inter-personal skills, excellent oral & written communication skills.Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.
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