Production Shift Incharge

2 weeks ago

Vizag, Andhra Pradesh, India Laurus Bio Full time ₹ 6,00,000 - ₹ 18,00,000 per year

Job Summary:

The Production Shift In-Charge USP is responsible for leading and supervising all upstream production activities during the assigned shift. This includes overseeing Microbial / mammalian operations, ensuring compliance with cGMP and safety standards, managing manpower, and ensuring smooth execution of the batch as per the production schedule and approved procedures.

Role & responsibilities

1. Shift Operations Management

  • Supervise and coordinate all upstream (USP) production activities during the shift, including media preparation, seed train, bioreactor operations, and harvest.
  • Ensure adherence to batch manufacturing records (BMR), SOPs, and GMP guidelines.
  • Monitor and record all process parameters (pH, DO, temperature, agitation speed, etc.) and ensure deviations are promptly reported and documented.
  • Review shift logbooks and ensure proper handover between shifts.

2. Team Leadership & Training

  • Lead, guide, and supervise operators, executives, and technicians in the USP area.
  • Allocate manpower and ensure optimal utilization of resources during the shift.
  • Train team members on cGMP, aseptic techniques, and safe handling of equipment and materials.

3. Equipment & Process Management

  • Ensure availability, cleanliness, and readiness of all USP equipment (bioreactors, autoclaves, incubators, fermenters, etc.).
  • Oversee CIP (Clean-In-Place) and SIP (Sterilize-In-Place) operations.
  • Coordinate with Engineering for preventive maintenance, calibration, and troubleshooting of equipment.
  • Verify line clearance before initiating batch operations.

4. Compliance & Documentation

  • Ensure that all operations comply with cGMP, EHS, and company policies.
  • Review batch records, logbooks, and cleaning records for completeness and accuracy.
  • Report deviations, non-conformances, and ensure timely initiation of CAPA.
  • Participate in internal and external audits as a process representative.

5. Coordination & Communication

  • Collaborate with QA, QC, Downstream Processing (DSP), and Warehouse teams for smooth batch execution.
  • Communicate critical issues, process alarms, or safety incidents to the Production Manager immediately.
  • Participate in daily production meetings and contribute to process improvements.

Preferred candidate profile

Key Competencies:

  • Leadership and team management skills.
  • Strong problem-solving and decision-making ability.
  • Excellent communication and documentation skills.
  • Attention to detail and commitment to compliance.
  • Ability to work in rotating shifts and under pressure.

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