Scientist 3
5 days ago
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- M. Pharm (Pharmacology / Pharmaceutical Analysis) / M.Sc. (Biochemistry / Pharmaceutical Chemistry) with 7-10 years or Ph.D. with 2-5 years' experience
- Expertise in designing and execution of DMPK studies to support ADC as well as antibody programs
- Extensive experience on quantification of antibodies, therapeutic protein, ADC and peptides using LC-MS/MS or MSD or ELISA.
- Well versed with handling of BioPharma finder, Maxquant, Spectronaut and other relevant software
- Leverage current and new techniques for function-based identification and selection of antibody-drug-conjugate (ADC), mAb lead drug candidates with the understanding of their DMPK properties, ensuring the safe and effective delivery of novel therapeutics.
- Interpret DMPK data and provide insights to project teams.
- Represent the group in internal and external meeting.
- Maintain strong relationship with other departments to understand ADC challenges and propose solutions from target concept to IND stage
- Responsible for preparation of relevant SOP, protocols, reports, etc. to support various regulatory and non-regulatory submission.
Strong understanding of various concepts of DMPK including PK-PD, tox and excellent communication skills, driving innovation, managing teams is added advantage
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