Walk-in Research Scientist

6 days ago

Udaipur, Rajasthan, India PI Industries Full time ₹ 1,04,000 - ₹ 1,30,878 per year

Key Responsibilities:

Strategic

  • Actively imbibing the values and philosophy of PI Industries.
  • Efficient contribution to the overall success of product innovation (PRI) through scientific contribution to objectives and targets being set by the leadership team.
  • Fullfilling requirements and achieveing goals set by the Team Leader and Group Leader
  • Working as a team member, contributing to the team objective with special focus on achiving and exceeding the set target.
  • Development of individual & team strengths by attending trainings based on the regular feedback as an individual and as a team

Operational

  • Monitoring reaction masses using LCMS/GCMS.
  • Execution of purity assessment and assay determination of samples using GC/HPLC/UFLC.
  • Able to carry method development for challenging compounds through GC/GCMS/HPLC/UFLC
  • Developing methods on Prep HPLC for purification/isolation of impure compounds.
  • Elucidating and confirming structures using NMR, FTIR and LCMS/MS
  • Ensure the scheduled performance of calibrations, Preventive maintenance and troubleshooting of core analytical instrument.
  • Following the set instrument maintenance practices like periodic solvent changes, system flushing, etc.
  • Assist the other team members in day to day activities like sample preparation, method developments, report generation and data management.
  • Following safety practices with out fail.

Financial

  • Planning the activities with existing resources and infra structure.
  • Suggesting the cost-effective areas to the Team Leader / Group Leader
  • Developing methods to improve the environment safety and to reduce the cost.

People

  • Collaborate with team members and cross functional teams to meet research objectives.
  • Develop and foster positive relationships with other teams and support groups to maximize cooperation and consequent benefit to objective delivery
  • Should be able to work in multitasking environment
  • Ensure team harmony through collaboration and active participation in all team discussion

Apart from the above responibilities, specific responsibilities of Research scientists

Note : The Associate would in any of the areas listed below based on the requirement and should have sufficient knowledge and expertise in the area alloted as listed below

1. HPLC/UFLC

  • Candidate should be well versed with normal and reverse phase chromatography techniques.
  • Able to optimize chromatographic methods
  • Keen knowledge on low level analyte-impurities quantification by HPLC.

2. LCMS SQD & TQD

  • Well versed with operations of one or more makes of LCMS-SQD & TQD instruments.
  • Aware of basic principles related to mass spectrometry, sources, analysers and detectors.
  • Hands on experience in analysis of compounds using LCMS instrument and releasing the mass confirmation reports.
  • Keen knowledge on ppb / ppm level quantification of analytes from AI, formulations, various matrices like microsomes, soil, plant extracts by LCMSMS.
  • Perform possible structural elucidation/Identification of degradants/metabolites/impurities using LCMS/MS

3. NMR

  • Perform suitable 1D/2D NMR experiments based on the requirement and confirm one among proposed structures or propose a new structure.
  • Manage the NMR activities viz, perform routine NMR (1D&2D) analysis, QNMR, cryogen replenishing.
  • Keen knowledge of NMR technology & instrument maintenance.

4. Physchem assays

  • Have hands on knowledge of various in vitro ADME/ physchem assays like solubility, LogP, pKa and in vitro Metabolic stability assay.
  • Able to develop methods, check method compatibility for accuracy, precision, matrix effect and apply it further for the quantification of formulations, plant extracts, various matrices like soil, microsomes etc.
  • Perform the microsomal stability experiments to determine half-life and Clint. Awareness about Met ID using various scans, fragmentation tree & HRMS will be an added advantage.
  • Knowledge about sample preparation and analysis of photo stability and hydrolytic stability.

5. Prep-HPLC

  • Able to develop a robust chromatographic method both at analytical and preparative scale, by designing cost effective methods for chiral and achiral molecules.

Knowledge of chiral chromatography and isolation of enantiomers using preparative HPLC.

Please share updated resume on e-mail id

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