Principal AI Engineer

Regeneron is founded on the belief that the right idea, combined with the right team, can lead to significant transformations. Our growing global network is dedicated to inventing, developing, and commercializing medicines that change lives for those with serious diseases. In doing so, we are pioneering innovative approaches to science, manufacturing, and commercialization, as well as redefining our understanding of health.

Regeneron is seeking a skilled Principal AI/ML Engineer to work as a technical lead for our artificial intelligence initiatives and drive strategic innovation across our research and development portfolio. As a Principal AI/ML Engineer, you will be responsible for owning the team for architecting and building enterprise-scale AI solutions that transform how we approach drug discovery, clinical research, and patient care. In the role you will work collaboratively with data scientists, researchers, and software engineers to architect, design, develop, and deploy cutting-edge AI solutions, addressing a range of business challenges. You will be instrumental in building and maintaining machine learning models, crafting advanced algorithms, and ensuring the scalability and robustness of our AI systems.

A Typical Day Might Include The Following

• Be responsible for the evaluation, adoption, and integration of emerging AI technologies and methodologies across the organization
• Architect and be responsible for the development of large-scale, distributed AI systems capable of processing multi-modal biological data
• Architect, Design, develop, and deploy AI models, algorithms, and systems to analyze sophisticated biological and pharmaceutical data.
• Collaborate with multi-functional teams to identify AI opportunities and chip in to project goals, requirements, and work you're doing.
• Create and maintain machine learning models, developing advanced algorithms for tasks such as image analysis, natural language processing, and predictive modeling.
• Design and optimize data pipelines and workflows for efficient data collection, preprocessing, and storage for AI training and evaluation.
• Adhere to standard methodologies in AI model development, deployment, and maintenance, with a focus on performance, scalability, reliability, and regulatory compliance.
• Stay abreast of the latest AI advancements, assessing their potential application and promoting innovation within the organization.
• Engage with external partners to integrate modern AI technologies and tools.
• Share a point of view in AI-related discussions, presenting findings and insights to partners.
• Implement and refine pioneering machine learning models and deep learning architectures.
• Use statistical techniques and data visualization to analyze and interpret AI model outputs, delivering insights to partners.
• Optimize AI models for performance and reliability, considering computational and regulatory constraints.
• Chip in to the development of AI-related procedures, standards, and guidelines within the organization.
• Participate in scientific and technical discussions, presenting findings to various audiences.
• Develop and maintain comprehensive documentation for AI models and systems.
• Communicate sophisticated AI concepts to non-technical partners.
• Mentor and guide senior AI/ML engineers, data scientists, and multi-functional teams in sophisticated AI methodologies
• Lead technical reviews, architectural decisions, and code quality standards across AI projects
• Translate sophisticated AI concepts into business value propositions for non-technical audiences
• Establish partnerships with technology vendors, cloud providers, and AI research organizations

This Job Might Be For You If You

• Bachelor's, Master's, or Ph.D. degree in Computer Science, Artificial Intelligence, Data Science, or a related field.
• At least 7 years of experience in AI/ML engineering, preferably within the biotechnology, pharmaceutical, or healthcare industry.
• Proven track record in biotechnology, pharmaceutical, or healthcare AI applications with measurable business impact
• Hands on experience in Building Generative AI solutions from scratch using frameworks such as LangChain, LangGraph, CrewAI
• Profound knowledge of large language models, including prompt engineering, fine-tuning, and retrieval-augmented generation (RAG)
• Extensive experience with cloud-native AI platforms (AWS SageMaker, Google Vertex AI, Azure ML) and containerization technologies
• Profound knowledge of AI governance frameworks, ethical guidelines, and regulatory compliance standards for biotechnology applications
• Profound knowledge of machine learning algorithms, deep learning frameworks (e.g., TensorFlow, PyTorch), and statistical methods.
• Proficient programming skills in languages such as Python, Java, R and familiarity with software engineering practices.
• Practical experience in and deploying AI models.
• Familiarity with Agentic AI patterns: ReAct, tool use, planning strategies, memory management, etc.
• Excellent communication developing skills and the ability to collaborate optimally with multi-functional teams.
• Strong problem-solving skills and a results-driven approach.
• Understanding of regulatory compliance related to AI in the biotech and pharma industries is advantageous.
• Knowledge of natural language processing techniques and tools.
• Demonstrated ability to lead and inspire high-performing technical teams
• Exceptional communication skills with experience presenting to C-level executives and external stakeholders
• Proven track record of driving organizational change and technology adoption
• Familiarity with big data technologies, such as Hadoop, Spark, or NoSQL databases.
• Experience with Dataiku, Databricks and AWS Sage maker
• Experience with OpenAI, Anthropic and other Generative AI Models
• Knowledge of the biotechnology and pharmaceutical industry is a plus.

Connect with us, so we can learn more about you, and you can learn more about our medicines. And join us in crafting the future of healthcare.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels For additional information about Regeneron benefits in the US, please visit For other countries' specific benefits, please speak to your recruiter.

Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron's roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron's on-site policy and expectations for your role and your location.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.