Research And Development Trainee

2 days ago

Hyderabad, Telangana, India Aurore Life Sciences Full time ₹ 5,00,000 - ₹ 15,00,000 per year

Job Purpose:

To carry out literature surveys, design synthetic routes, and perform multi-step organic synthesis for development and optimization of API molecules in line with regulatory and project timelines.

Location: Hyderabad

Department: Research & Development (R&D) API Division

Reporting to: Manager

Experience: 05 years (adjust based on requirement)

Education: M.Sc. in Organic Chemistry

Key Responsibilities:

  • Route Design and Synthesis:

  • Conduct literature and patent searches (e.g., using SciFinder, Reaxys).

  • Propose and develop synthetic routes for new and existing APIs.

  • Synthesize intermediates and APIs on lab scale.

  • Process Development:

  • Optimize reactions for yield, purity, and scalability.

  • Participate in scale-up activities from lab to kilo lab and pilot plant.

  • Develop cost-effective and environmentally friendly processes.

  • Analytical Support:

  • Work with Analytical R&D to characterize synthesized compounds (e.g., NMR, HPLC, GC, IR, MS).

  • Prepare samples for stability and impurity profiling.

  • Documentation:

  • Maintain accurate and detailed lab notebooks.

  • Draft technical documents: process development reports, technology transfer dossiers, etc.

  • Ensure compliance with regulatory guidelines (ICH, GMP, etc.).

  • Collaboration:

  • Interact with cross-functional teams Analytical, Regulatory Affairs, QA/QC, and Manufacturing.

  • Support technology transfer to manufacturing locations.

Key Skills and Competencies:

  • Strong theoretical and practical knowledge in organic synthesis and reaction mechanisms.
  • Familiarity with GMP practices, regulatory norms (ICH Q11, Q7).
  • Experience in reaction optimization, purification techniques, and problem solving.
  • Proficiency in tools like SciFinder, Reaxys, and analytical instruments (HPLC, NMR, GC).
  • Good communication skills and teamwork orientation.
  • Ability to handle multiple projects and meet tight deadlines.

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