Research and Senior Research Associate

3 days ago

Ahmedabad, Gujarat, India o2h Group Full time ₹ 8,00,000 - ₹ 12,00,000 per year

Synthesis R&D:

  • Responsible to perform routine organic synthesis. (mg to gram scale) & work independently under the guidance of the leader.

  • Independently support the scientific team with instrumentation and equipment operation and maintenance.

  • Able to understand & interpret various instruments like NMR, Mass, HPLC.

  • Instrument purification like Combiflash, big columns, column packing. Deciding the mobile phase for purification.

  • Independently handling all types of glassware assembly arrangement, reaction reagent charging, maintaining temperature, nitrogen, etc.

  • Should be able to understand the written instruction from the scientist including patents and reprints where procedure highlighted by scientists.

  • To train and support the team members.

  • Meticulous Documentation & proper data management.

  • To maintain the record book of the work done like purification or reaction.

ADC (Antibody Drug Conjugate) R&D

  • Synthesis and purification of complex antibody drug conjugate (ADC) molecules

  • Synthesis of different type of linkers - using natural and un-natural amino acids, PEGs

  • Synthesis of high potent drug molecules – payloads

  • Purification of complex and large molecules by flash column and HPLC

  • Handling various type chemistry with different payloads

  • Interpretation and characterization of higher molecular weight compounds

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