Walk in For AR&D positions
2 weeks ago
Dear Candidate,
We are Conducting Walk -In for the positions in our Analytical Research & Development department.
Job Description:
Position Name: Research Chemist/Senior Research Chemist/Research Associate
Experience: 1 to 5 years
Qualification: M.Sc Analytical Chemistry/Organic
Work location: Uppal/Mallapur
Key Skills and Competencies:
High-Performance Liquid Chromatography (HPLC)
Key Skills and Competencies:
- Operation and Maintenance: Proficiency in operating HPLC systems (e.g., Agilent, Waters, Shimadzu) and performing routine maintenance, calibration, and troubleshooting of equipment issues like pressure fluctuations or detector errors.
- Method Development and Validation: Ability to develop and optimize HPLC methods for analyzing small molecules, impurities, or degradation products, adhering to ICH guidelines (e.g., ICH Q2 for validation).
- Data Analysis: Expertise in interpreting chromatograms, quantifying analytes, and using software like Empower or ChemStation for data processing and reporting.
- Sample Preparation: Skilled in preparing samples (e.g., dissolution, extraction) for pharmaceutical or chemical analysis, ensuring reproducibility and accuracy.
- Regulatory Compliance: Knowledge of Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP) for documentation, method validation, and audit readiness.
- Troubleshooting: Ability to diagnose and resolve issues such as peak tailing, baseline drift, or column degradation.
Experience Level (1-5 Years):
- 1-2 years: Basic operation, routine analysis, and data interpretation under supervision.
- 3-5 years: Independent method development, validation, and troubleshooting with familiarity in handling complex matrices.
Prep HPLC
Key Skills and Competencies
Operation and Maintenance
- Hands-on experience with Preparative HPLC systems (e.g., Agilent, Waters, Shimadzu, GE KTA).
- Proficiency in system setup, gradient programming, scale-up from analytical to preparative runs.
- Routine maintenance and calibration of pumps, fraction collectors, and detectors.
- Troubleshooting common issues such as pressure fluctuations, air bubbles, or pump leakage.
Purification & Method Development
- Strong background in method development and optimization for preparative HPLC to isolate target compounds (APIs, impurities, natural products, metabolites, peptides).
- Experience in scaling up analytical methods to preparative scale while ensuring recovery, purity, and yield requirements.
- Knowledge of different stationary phases (C18, C8, size-exclusion, chiral) and selection of appropriate mobile phases.
Sample Preparation & Fraction Collection
- Skilled in preparing crude samples (reaction mixtures, fermentation broths, plant extracts) for scalable purification.
- Competence in managing fraction collection strategies, solvent recovery, and sample lyophilization/drying.
- Ensuring high-quality isolation of compounds with reproducibility.
Data Analysis & Reporting
- Ability to interpret chromatograms, verify purity and recovery using both analytical HPLC/UPLC and complementary techniques (LC-MS, NMR).
- Proficiency in software like ChemStation, Empower, Unicorn, or equivalent for processing preparative runs and reporting results.
- Documentation of purification workflows in compliance with client and regulatory requirements.
Regulatory Compliance & CRO Environment
- Knowledge of Good Laboratory Practices (GLP) and CRO industry requirements for method documentation, record-keeping, and reproducibility.
- Familiarity with client-driven project timelines and requirements.
- Experience preparing project reports, tech-transfer documents, and audit-ready records.
Troubleshooting & Continuous Improvement
- Expertise in diagnosing issues like sample overload, poor recovery, carry-over, baseline instability, or column degradation.
- Ability to suggest process improvements for higher throughput and purity levels.
Experience Level (Typical Range: 1-5 Years)
1-2 years:
Basic operation of preparative HPLC systems.
- Performing routine purification runs under supervision.
Basic troubleshooting and hands-on sample preparation.
3-5 years:
Independent purification and method development for wide compound classes.
- Competent in scale-up from analytical to preparative levels.
- Handling of challenging crude matrices and optimization of recovery/yield.
- Active participation in client projects, troubleshooting, and mentoring junior team members.
Walk-In interview Date - 26th Sept 2025
Timings:-
between 09 AM to 12 PM.
Venue:
Chemveda Life Sciences,
Admin Building,1st floor IDA Uppal,
Uppal, Hyderabad, Telangana 500039
Contact Person - Sai Vardhan
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