Walk in For AR&D positions

2 weeks ago


Hyderabad Mallapur Uppal, India Chemveda Life Sciences Full time ₹ 2,50,000 - ₹ 12,00,000 per year

Dear Candidate,

We are Conducting Walk -In for the positions in our Analytical Research & Development department.

Job Description:

Position Name: Research Chemist/Senior Research Chemist/Research Associate

Experience: 1 to 5 years

Qualification: M.Sc Analytical Chemistry/Organic

Work location: Uppal/Mallapur

Key Skills and Competencies:

High-Performance Liquid Chromatography (HPLC)

Key Skills and Competencies:

  • Operation and Maintenance: Proficiency in operating HPLC systems (e.g., Agilent, Waters, Shimadzu) and performing routine maintenance, calibration, and troubleshooting of equipment issues like pressure fluctuations or detector errors.
  • Method Development and Validation: Ability to develop and optimize HPLC methods for analyzing small molecules, impurities, or degradation products, adhering to ICH guidelines (e.g., ICH Q2 for validation).
  • Data Analysis: Expertise in interpreting chromatograms, quantifying analytes, and using software like Empower or ChemStation for data processing and reporting.
  • Sample Preparation: Skilled in preparing samples (e.g., dissolution, extraction) for pharmaceutical or chemical analysis, ensuring reproducibility and accuracy.
  • Regulatory Compliance: Knowledge of Good Manufacturing Practices (GMP) and Good Laboratory Practices (GLP) for documentation, method validation, and audit readiness.
  • Troubleshooting: Ability to diagnose and resolve issues such as peak tailing, baseline drift, or column degradation.

Experience Level (1-5 Years):

  • 1-2 years: Basic operation, routine analysis, and data interpretation under supervision.
  • 3-5 years: Independent method development, validation, and troubleshooting with familiarity in handling complex matrices.

Prep HPLC

Key Skills and Competencies

Operation and Maintenance

  • Hands-on experience with Preparative HPLC systems (e.g., Agilent, Waters, Shimadzu, GE KTA).
  • Proficiency in system setup, gradient programming, scale-up from analytical to preparative runs.
  • Routine maintenance and calibration of pumps, fraction collectors, and detectors.
  • Troubleshooting common issues such as pressure fluctuations, air bubbles, or pump leakage.

Purification & Method Development

  • Strong background in method development and optimization for preparative HPLC to isolate target compounds (APIs, impurities, natural products, metabolites, peptides).
  • Experience in scaling up analytical methods to preparative scale while ensuring recovery, purity, and yield requirements.
  • Knowledge of different stationary phases (C18, C8, size-exclusion, chiral) and selection of appropriate mobile phases.

Sample Preparation & Fraction Collection

  • Skilled in preparing crude samples (reaction mixtures, fermentation broths, plant extracts) for scalable purification.
  • Competence in managing fraction collection strategies, solvent recovery, and sample lyophilization/drying.
  • Ensuring high-quality isolation of compounds with reproducibility.

Data Analysis & Reporting

  • Ability to interpret chromatograms, verify purity and recovery using both analytical HPLC/UPLC and complementary techniques (LC-MS, NMR).
  • Proficiency in software like ChemStation, Empower, Unicorn, or equivalent for processing preparative runs and reporting results.
  • Documentation of purification workflows in compliance with client and regulatory requirements.

Regulatory Compliance & CRO Environment

  • Knowledge of Good Laboratory Practices (GLP) and CRO industry requirements for method documentation, record-keeping, and reproducibility.
  • Familiarity with client-driven project timelines and requirements.
  • Experience preparing project reports, tech-transfer documents, and audit-ready records.

Troubleshooting & Continuous Improvement

  • Expertise in diagnosing issues like sample overload, poor recovery, carry-over, baseline instability, or column degradation.
  • Ability to suggest process improvements for higher throughput and purity levels.

Experience Level (Typical Range: 1-5 Years)

  • 1-2 years:

  • Basic operation of preparative HPLC systems.

  • Performing routine purification runs under supervision.
  • Basic troubleshooting and hands-on sample preparation.

  • 3-5 years:

  • Independent purification and method development for wide compound classes.

  • Competent in scale-up from analytical to preparative levels.
  • Handling of challenging crude matrices and optimization of recovery/yield.
  • Active participation in client projects, troubleshooting, and mentoring junior team members.

Walk-In interview Date - 26th Sept 2025

Timings:-

between 09 AM to 12 PM.

Venue:

Chemveda Life Sciences,

Admin Building,1st floor IDA Uppal,

Uppal, Hyderabad, Telangana 500039

Contact Person - Sai Vardhan


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