Postdoctoral Fellow/Scientist, Structural Biology
1 week ago
Key Responsibilities:
- Apply deep domain knowledge in structural biology to characterize macromolecular complexes and understand their roles in disease pathways.
- Integrate structural insights with multi-omics data (genomics, transcriptomics, proteomics, and metabolomics) to understand molecular mechanisms of disease.
- Utilize and develop computational tools for structural modeling, molecular dynamics simulations, and ligand docking to complement experimental data.
- Stay up to date with the latest advancements in structural biology, biophysics, and computational methods to incorporate cutting-edge research into disease modeling efforts.
Collaboration & Project Management:
- Work closely with cross-functional teams, including disease domain experts, computational scientists, and clinicians to enhance translational research efforts.
- Work with the Scientific Manager to help in project planning, execution, and reporting, ensuring alignment with research objectives.
- Communicate findings effectively through reports, presentations, and discussions with internal teams and external collaborators.
- Publish research findings in high-impact, peer-reviewed journals.
- Present work at scientific conferences, symposia, and internal research meetings.
- Contribute to grant applications and funding proposals where relevant.
Qualifications & Experience:
- PhD in structural biology, biophysics, biochemistry, or a closely related field.
- Strong expertise in at least one major structural biology technique (e.g., X-ray crystallography, cryo-electron microscopy (cryo-EM), NMR spectroscopy).
- Solid understanding of protein structure-function relationships, macromolecular interactions, and their relevance to disease biology.
- Experience in experimental design, data collection, data processing, and structure determination.
- Excellent verbal and written communication skills, with the ability to convey complex structural biology concepts clearly.
Preferred:
- Experience with computational structural biology tools (e.g., Rosetta, AlphaFold, molecular dynamics software).
- Previous experience working in a multidisciplinary research environment.
- Familiarity with AI/ML approaches in structural biology or drug discovery.
Other Considerations:
- Fresh PhD graduates will be hired as Postdoctoral Fellows for a two-year term with an opportunity for promotion to Scientist based on performance.
- Candidates with at least two years of postdoctoral experience in structural biology in either academia or industry will be hired as Scientists with opportunities for career advancement.
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