Executive - API R&D

5 days ago

Vadodara, Gujarat, India SUN PHARMA Full time US$ 60,000 - US$ 1,20,000 per year

Role
To execute activities related to R&D Peptide Process Development & Scale-ups, along with a group comprising of Research Officers/ Research Assistants in co-ordination with Team/Group Leader

Details Of Previous Work Experience (Mandatory Requirement)

  • Literature search and ROS (Route of Synthesis) finalization
  • Basic knowledge of Orthogonal protected amino acid and Peptide
  • Solid phase peptide Synthesis/Oligonucleodtide Synthesis
  • Handling of hazardous chemical like Trifluoroacetic acid
  • Knowledge of handling of analytical HPLC/Oligo Synthesis
  • Purification using Preparative HPLC
  • Preparative column packing and usage.
  • Computer literacy etc.
  • Knowledge of Phosphoramidalin /handling/storage

Job Description

  • Literature search with respect to assigned project and finalizing the non-infringing synthetic route
  • Experimentation (Process development, DoE study, optimization and validation).
  • Purification of Peptide and knowledge of lyophilisation of pure solution.
  • Handling of analytical HPLC and preparation of buffer.
  • Characterisation of Peptide using HRMS,2D NMR, IR, Peptide mapping and sequencing.
  • Preparation of Technology transfer documents.
  • Scaling-up of process developed at R&D.
  • Assisting to RA in filing DMF.
  • General Laboratory Management etc.

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