
Senior Researcher in Medicinal Chemistry
22 hours ago
Job Title: Senior Researcher in Medicinal Chemistry
Job Description:
We are seeking a highly skilled Senior Scientist with expertise in Design, Monitoring, Preclinical and Clinical (DMPK) studies to support our antibody-drug conjugate (ADC) and monoclonal antibody (mAb) programs.
- DMPK Expertise: Expertise in designing and executing DMPK studies to support ADC and mAb programs, including quantification of biologics using LC-MS/MS, MSD, and ELISA platforms.
- Advanced Bioinformatics Tools: Proficient in tools such as BioPharma Finder, MaxQuant, Spectronaut, and other relevant analytical software.
- Lead Candidate Identification: Skilled in applying innovative techniques for function-based identification and selection of ADC and mAb lead candidates with a strong focus on DMPK profiling.
- Data Interpretation: Experienced in interpreting complex DMPK data and providing actionable insights to cross-functional project teams.
- Cross-Functional Collaboration: Actively represent DMPK functions in internal and external meetings, fostering collaboration and strategic alignment.
- Regulatory Compliance: Accountable for authoring and reviewing SOPs, study protocols, reports, and regulatory documentation to support GLP and non-GLP studies.
Competencies:
- Antibody Characterization: Strong foundational knowledge of DMPK principles, including PK/PD, toxicology, and translational sciences.
- Communication Skills: Demonstrated capabilities in communication, innovation, and team leadership.
About the Opportunity: We offer a dynamic and innovative work environment that fosters collaboration and growth.
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