Protein Purification Specialist

5 days ago

Bengaluru, Karnataka, India Syngene Full time

Job Title: Team Lead - Biologics

Location: Bangalore

Department: Discovery Biology

Job Summary: We are seeking a highly motivated and experienced Team Lead - Biologics to join our team at Syngene.

Key Responsibilities:

  • Protein purification and quality check (SDS-PAGE, SE-HPLC)
  • Protein purification optimization and protocol development using AKTA systems as well as batch purification method
  • Regularly prepare detailed records of experiments, reports and presentations
  • Manage multiple projects simultaneously under strict deadlines
  • Help other team members in their work, troubleshooting
  • Contribute in general lab cleanliness and equipment maintenance

Requirements:

  • Excellent theoretical knowledge of proteins, biochemistry and various methods of protein purification – affinity, ion exchange and size exclusion
  • Solid working knowledge of making buffers and solutions, calculations of molarity, dilutions, measuring pH of solutions
  • Proven hands-on experience and technical expertise in using AKTA systems (pure, primePlus, explorer, start)
  • Excellent verbal and written communication and interpersonal skills
  • Ability to work independently as well as in a team environment
  • Ability to manage multiple projects in parallel and coordination of internal and external resources is essential
  • Strong organizational, detail-orientation, prioritization and multi-tasking skills
  • Attention to detail, strong analytical skills and ability to work under strict timelines
  • Ability to properly document results and observations in timely manner, make presentations
  • Personal attributes – organized, motivated, cooperative, friendly, respectful and communicative

Desirable Qualifications:

  • Knowledge and experience in analytical techniques – mass spectrometry, SE-HPLC, protein stability studies
  • Knowledge of purification of antibodies and proteins from inclusion bodies
  • Knowledge and hands-on experience with packing customized columns
  • Ability to train other junior members in the team

Education & Experience: PhD in life science/biochemistry/biotechnology with 3-6 years

Syngene Values:

Accountabilities as a Syngene Leader:

  • Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business.
  • Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.
  • Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.

Behavioral / Managerial skills:

  • Demonstrated capabilities in leading a team and working in a matrix environment. Ability to rationally discuss data make data-driven decisions, and influence decisions to select optimal molecules for development. Ability to work in collaboration with a large inter-disciplinary team and assimilate data from various aspects. Excellent communication and presentation skills
  • Experience managing multiple complex projects simultaneously requiring frequent communication, organizing/time management, and problem-solving skills
  • Excellent interpersonal, communication, collaboration, analytical, and scientific project management skills
  • Ability to work with senior management with professionalism and discretion

Equal Employment Opportunity: It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

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