Research Scientist
3 days ago
Syngene International Limited seeks an experienced Research Scientist with expertise in Neuropharmacology to join their Molecular Pharmacology group. As a key member of the team, you will contribute to the discovery and validation of therapeutic targets and participate in drug discovery programs focused on neuropsychiatric diseases.
Responsibilities
Design and conduct rigorous experiments using cell-based assays and biochemical methods to execute discovery programs. Perform occupancy assays to analyze changes in target engagement from cell cultures, brain, and peripheral tissues. Independently develop and troubleshoot assays, record, analyze, and communicate scientific data. Ensure the accuracy and reliability of data by searching and reviewing the scientific literature independently on target biology.
Requirements
MS, MTech, or MPharm in enzymology, biochemistry, molecular biology, or related disciplines. 5-6 years of experience in neuropharmacology/small molecule pharmacology at therapeutically relevant GPCRs/neurotransmitter receptors at the molecular level in the CNS. Demonstrated technical proficiency in biochemical, cellular, and/or radioligand binding assay systems to assess drug target engagement. Ability to perform ex-vivo receptor occupancy assays in brain tissues to understand receptor-targeted drug efficacies. Hands-on experience in complex cellular models/ex-vivo systems, including designing and executing mechanistic/pharmacological characterization of lead candidates.
What We Offer
A competitive salary range of $80,000 - $110,000 per annum, depending on qualifications and experience. The opportunity to work with a global discovery, development, and manufacturing organization providing integrated scientific services to various industries. Strong problem-solving and data analysis skills, excellent written and verbal communication skills, good presentation skills, and the ability to handle multiple projects simultaneously and meet aggressive project timelines. Syngene is an equal opportunity employer committed to diversity and inclusion.
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