Probiotics Manufacturing Specialist

3 weeks ago

Coimbatore, Tamil Nadu, India 4miZyme Bioscience Pvt. Ltd Full time
Job Title: Manufacturing Lead – Probiotics

We are seeking an experienced Manufacturing Lead to spearhead the establishment and scaling of our fermentation facility. As a newly launched company in the probiotics space, we are looking for a candidate with both technical expertise and hands-on experience in setting up and scaling fermentation operations, who can guide us from facility setup to full-scale production.

Key Responsibilities:

Facility Setup:

  • Lead the design, setup, and commissioning of the fermentation facility, including equipment selection, installation, and validation.
  • Work closely with engineers, consultants, and vendors to ensure that all fermentation-related infrastructure meets industry standards and regulatory compliance.
  • Develop and implement operational procedures for the fermentation unit.

Fermentation & Manufacturing Operations:

  • Oversee daily fermentation operations, ensuring the efficient production of probiotics, including Lactobacillus, Bifidobacterium, and Saccharomyces species.
  • Manage and optimize upstream fermentation processes from small to large-scale production (including 15 cubic meter capacity), ensuring yield and quality consistency.
  • Scale-up fermentation processes from pilot to commercial scale.

Process Development & Scale-Up:

  • Lead the fermentation scale-up efforts, including optimizing bioprocess parameters and ensuring smooth transitions from lab-scale trials to commercial production.
  • Develop robust protocols for the fermentation process, including monitoring critical process parameters, inoculation procedures, and media optimization.
  • Implement continuous improvement initiatives to enhance efficiency, reduce costs, and increase production capacity.

Quality Control & Compliance:

  • Ensure that all fermentation processes comply with cGMP, ISO, and other relevant industry standards for probiotic production.
  • Work with the Quality Assurance team to maintain rigorous quality control throughout the fermentation process.
  • Ensure proper documentation, batch records, and regulatory submissions related to fermentation and scale-up activities.

Team Leadership & Collaboration:

  • Manage a cross-functional team of engineers, biotechnologists, and production staff to achieve project goals.
  • Train and mentor junior team members, providing technical guidance on fermentation practices and production processes.
  • Collaborate with R&D, quality assurance, and supply chain teams to ensure smooth operational integration and product quality.

Equipment & Maintenance:

  • Oversee the maintenance, calibration, and troubleshooting of fermentation equipment.
  • Implement best practices in preventive maintenance to minimize downtime and ensure the longevity of fermentation equipment.

Key Qualifications:

  • Bachelor's or Master's degree in Biotechnology, Microbiology, Bioprocess Engineering, Chemical Engineering, or a related field.
  • 7+ years of experience in fermentation, preferably with probiotics products.
  • Proven experience in setting up and scaling fermentation facilities from scratch.
  • Strong understanding of upstream fermentation processes, bioreactor operation, and process optimization.
  • Experience in managing large-scale fermentation systems (up to 5 cubic meters and above).
  • Familiarity with cGMP and other regulatory standards in the probiotic or biopharmaceutical industry.
  • Hands-on experience with bioreactor equipment, drying processes (lyophilization, spray drying), and downstream processing techniques.
  • Excellent leadership and project management skills, with the ability to collaborate across teams and departments.
  • Strong problem-solving abilities and a focus on process improvement.

Preferred Qualifications:

  • Experience in probiotic manufacturing or similar microbial fermentation processes.
  • Knowledge of ISO certification processes and regulatory guidelines for probiotics production.
  • Strong understanding of scale-up challenges and bioprocess development.

Why Work with Us:

We are a newly launched probiotics manufacturing company, offering a unique opportunity to join a groundbreaking team and contribute to the establishment of a state-of-the-art fermentation facility. As a key member of our team, you will have the opportunity to grow with the company as we expand our operations and product offerings.

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