Research & Development: Opportunities in Characterization Development Lab

2 months ago

bangalore, India Biocon Biologics Full time

Biocon Biologics is a fully-integrated ‘pure play’ biosimilars organization globally committed towards transforming patient lives through innovative and inclusive healthcare solutions. It is engaged in developing high-quality, affordable biosimilars aimed at expanding patient access to cutting-edge class of therapies across the world. Biocon Biologics is a subsidiary of Biocon Ltd, an innovation led-global biopharmaceuticals company and India's first publicly listed biotech enterprise. Biocon Biologics has one of the largest biosimilars portfolios, a wide global footprint, state-of-the-art manufacturing facilities, world-class R&D ecosystem, and high quality & compliance standards, enabling it to fulfil unmet needs of patients across the globe.


Role Summary


  • Relevant experience in mass spectrometry-based characterization of monoclonal antibodies, insulin analogues, pegylated proteins, antibody-drug conjugates, therapeutic peptides, host cell proteins, polysorbates etc
  • Experience in handling high-resolution mass spectrometers (Q-TOF/Orbitrap) and familiarity with different software platforms for intact/subunit mass deconvolution, reduced and non-reduced peptide mapping, glycan analysis and other such biopharma applications
  • Experience with multi-attribute methods (characterisation and monitoring), new peak detection, generation of automated reports using new generation ‘MS only’ instruments
  • Demonstrated experience in analytical separations with strong chromatography background and willing to cross-learn new skills
  • Experience in mass-spec based host-cell protein identification and quantitation, higher-order structure determination using HDX-MS technology, top-down, middle-down and bottom-up approaches of mass spectrometry are desirable
  • Experience in biopharmaceutical MS software such as Proteome discoverer, Byonic, Biopharma finder, Protein pilot, Peakview etc, documentation software such eLN, LIMS, QMS software such Trackwise


Education & Experience - Post-graduate with 6-8 years of research experience or PhD with 3 to 5 years experience. Life sciences background in biochemistry, biotechnology, protein chemistry or allied subjects preferred

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