Computational Biologist

1 day ago

delhi, India Micro Crispr Pvt. Ltd. Full time

Job Title: Computational Structural Biologist

Experience: Fresher to 2 years

Location: Delhi


JD for Computational Structural Biology Team

We are seeking a talented and enthusiastic COMPUTATIONAL STRUCTURAL BIOLOGIST to join our innovative team. As part of our team, you will have the opportunity to work on cutting-edge projects that have a significant impact on patient care and medical research.


Responsibilities:

Computer aided drug discovery for hit identification.

Protein engineering

de novo protein design and computational evaluation

Develop and implement computational models to study protein structures.

Computational antibody engineering

Conduct molecular docking, dynamics simulations, and free-energy calculations.

Experience in handling protein structure prediction tools

Collaborate with experimental scientists to validate computational predictions.

Maintain and optimize computational pipelines for high-throughput analysis.

Data Analysis and Interpretation

Write and present research findings in scientific reports and publications/patents.


Required Skills:

Machine learning based platforms for protein engineering and modelling (AlphaFold, RFDiffusion, RosettaFold)

Generative AI for small molecule and peptide design


Qualification

Master's degree/PhD in Bioinformatics, Computational structural biology

Proficiency in programming languages such as Python or R, or Java.

Strong expertise in structural modeling tools (e.g., Rosetta, PyMOL, Chimera).

Experience in docking (Glide, AutoDock Vina, HADDOCK) and molecular dynamics simulations (AMBER, GROMACS. Desmond) etc

Experience in downstream analysis tools such as MMPBSA, FEP

Immunoinformatic, computational protein engineering tools


Soft Skills:

Ability to work independently and collaboratively in a team-based environment.

Excellent problem-solving skills and the ability to think critically and analytically.

Emphasize interpersonal and problem-solving skills.

Strong communication and teamwork abilities.

Critical thinking and attention to detail.

Ability to manage multiple projects and meet deadlines

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