BBRC - Research Investigator - Medchem CADD

1 month ago

bangalore, India Syngene International Limited Full time

JOB DESCRIPTION


Designation: Research Investigator (7-I) / Senior Research Investigator (7-II)

Job Location: Bangalore

Department: Medchem - CADD


About Syngene

Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene’ s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240 – strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation.

Job Purpose: To be a part of Medchem CADD team and provide comprehensive and impactful

computational chemistry support to drug discovery programs.


Key Responsibilities:

• Provide comprehensive and impactful computational chemistry support to drug discovery programs.

• Demonstrate an understanding of full spectrum of project structure-activity relationship (in vitro biology, DMPK, structural and computational).

• Work in close collaboration with medicinal chemists.

• Present plans, progress and results at CADD, chemistry and project team meetings.

• Identify and implement the best computational techniques to address specific problems.

• Maintain a good awareness of the literature related to the project and the discipline

• Maintain good records and provide data as required.


Educational Qualifications:

PhD in computational chemistry or computer aided drug discovery


Experience:

0-5 years of experience in pharmaceutical/Biotechnology industry.



Technical Skills:

• Proficiency in structure and ligand based computational approaches – theory: molecular mechanics

and quantum mechanics; Methods: docking, pharmacophore modelling, molecular dynamics

simulation, QM calculations.

• Proficiency in statistical methods

• Proficiency in physical organic chemistry

• Proficiency in Python and/or Unix Shell scripting

• Experience in working with interdisciplinary teams such as medicinal chemistry, biology and

DMPK scientist

• Experience in disease areas such as oncology, immunology, cardiovascular and fibrosis


Functional/Behavioral Skills:

• Strong interpersonal skills

• Strong communication skills

• Seek broader input / ask questions to understand bigger picture

• Active listening

• Offer help to solve team members’ work


Equal Opportunity Employer:

It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.

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