Associate Director, Pkpd

Job Title Associate Director PKPD Pharmacometric Data SAS ProgrammerCareer Level - EIntroduction to Role Are you ready to make a significant impact in the world of drug development We are seeking an Associate Director for PKPD Pharmacometric Data SAS Programmer belonging to the Clinical Pharmacology and Quantitative Pharmacology programming team This role focuses on all aspects of data preparation programming validation and diagnostics to support Pharmacometric and clinical pharmacology analyses at the study and project levels You will be instrumental in influencing critical decision making throughout all phases of drug development and regulatory interactions Accountabilities As an Associate Director you will be accountable for expert data integration manipulation and preparation results at the study and project level You will execute state-of-the-art data preparation techniques with direct value for the study and or project Your responsibilities will include collating cleaning and preparing analysis-ready data for Pharmacometric Modeling and Simulation M S software e g NONMEM to influence study designs and go no-go decisions You will also contribute to regulatory documents and interactions internal initiatives to develop the Pharmacometric discipline and compliance with Good Clinical Practice GCP regulations Essential Skills Experience 10 years of hands-on experience in SAS programming Strong understanding of pharmacokinetics pharmacodynamics and their application in drug development Strong SAS R programming skillsExpert knowledge of data preparation and programming practices CDISC SDTM ADaM Demonstrated data programming and clinical development expertiseGood knowledge of global regulatory compliance processes standardsCapability to develop tools to support data integration visualizationBachelors degree MS preferred with relevant experience requiredDemonstrated experience in regulatory submissions and interdisciplinary team leadershipVaried programming languages SAS R Python Experience in early and late-stage drug developmentExcellent problem-solving communication and project management skills Proficient oral and written English communication skillsKnowledge in pharmacology drug targets and core Therapy areas e g Oncology Respiratory Renal Metabolism etc Quantitative Scientific background Statistics Engineering Biological Science Desirable Demonstrated expertise in data preparation and programming to support Pharmacometric Modeling and Simulation M S software e g NONMEM Monolix R Matlab Scientific publishing in the field on pharmacometricsWhen we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing medicines In-person working gives us the platform we need to connect work at pace and challenge perceptions That s why we work on average a minimum of three days per week from the office But that doesn t mean we re not flexible We balance the expectation of being in the office while respecting individual flexibility Join us in our unique and ambitious world Why AstraZenecaJoin our Biopharmaceuticals R D team and be part of a team where you are empowered to follow the science At AstraZeneca we are unlocking the power of what science can do We are working towards treating preventing modifying and even curing some of the world s most complex diseases Here we have the potential to grow our pipeline and positively impact the lives of billions of patients around the world We are committed to making a difference and have built our business around our passion for science Now we are fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs Ready to make a difference Apply today and join us in pushing the boundaries of science to deliver life-changing medicines Date Posted 15-Jan-2025Closing Date 28-Feb-2025AstraZeneca embraces diversity and equality of opportunity We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills We believe that the more inclusive we are the better our work will be We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics We comply with all applicable laws and regulations on non-discrimination in employment and recruitment as well as work authorization and employment eligibility verification requirements