Scientist - Bioinformatics Data Curation (Remote, Contract)

4 weeks ago

India Synlico Inc. Full time
Synlico Inc., a Johnson & Johnson Innovation JLABS@SSF resident company, is at the forefront of transforming biology by leveraging causality to make cellular processes explainable, predictable, and engineerable. Our AI platform employs machine learning & deep learning, causal discovery & inference, and single-cell bioinformatics. Our unique approach lies in unraveling the causal relationships between cells' intracellular activities and their responses in the patients' heterogeneous microenvironment, predicting how cell modulation alters its behavior in patients. Our technology has a broad range of potential vertical applications in drug discovery, including target identification, therapy design, manufacturing, and biomarker discovery. Our HQ is in South San Francisco, CA, United States. For more information, please visit www.synlico.com.

We are seeking a Scientist - Bioinformatics Data Curation (Remote, Contract) to conduct searches in public databases and distinguish different functional genomics technologies and biological experimental methodologies. The role involves validating and entering accurate datasets, ensuring data consistency, and optimizing database structure for smooth information flow. The ideal candidate should have a strong focus on modern single-cell gene expression technologies and coding skills, demonstrate critical thinking, attention to detail, and consistency in delivering reliable results.

Job Description:

- Conduct searches in public genomic databases (GEO, CellXGene, HumanCell Atlas).
- Distinguish different functional genomics technologies and biological experimental methodologies to match the company's needs.
- Understand necessary dataset qualifications.
- Enter matching datasets to the database accurately with the utmost attention.
- Validate/cross-check new datasets to avoid duplicates or problems.
- Optimize database structure to optimize information flow.

Job Requirements:

- Ph.D graduate in computational biology, bioinformatics, single-cell biology, genomics, immunology, biomedical engineering, or a related field.
- A strong technical focus and knowledge of genomics, molecular biology, and technologies such as qPCR and next-generation sequencing
- Demonstrated proficiency in the analysis of large-scale transcriptomics data (especially scRNA-seq)
- Experience identifying outliers for gene expression and splicing from RNA-seq data
- Experience working with relevant genomic databases and browsers and their annotations
- Proficiency in Git operations
- Strong coding and visualization skills using Python or R.
- Experienced in data wrangling using pandas or tidyverse.
- Skilled in Linux command-line interface (CLI) operations.
- Attention to Detail: Ability to ensure accuracy and spot discrepancies or duplications for data entry and validation.
- Dig to the bottom: Ability to track down the correct data source and not be dissuaded by obstacles or incomplete information.
- Critical Thinking: Ability to assess, analyze, and question information critically is essential.
- Consistency: Ability to deliver steady and reliable results in a given time frame.
- Good command of English speaking and writing.

Total Contract Value (annual): Rs. 12L - 15L. Contractors are responsible for their own taxes.

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