Executive - API R&D

3 weeks ago


Vadodara India SUN PHARMA Full time

Job Description Role To execute activities related to R&D Peptide Process Development & Scale-ups, along with a group comprising of Research Officers/ Research Assistants in co-ordination with Team/Group Leader Details Of Previous Work Experience (Mandatory Requirement) - Literature search and ROS (Route of Synthesis) finalization - Basic knowledge of Orthogonal protected amino acid and Peptide - Solid phase peptide Synthesis/Oligonucleodtide Synthesis - Handling of hazardous chemical like Trifluoroacetic acid - Knowledge of handling of analytical HPLC/Oligo Synthesis - Purification using Preparative HPLC - Preparative column packing and usage. - Computer literacy etc. - Knowledge of Phosphoramidalin /handling/storage Job Description - Literature search with respect to assigned project and finalizing the non-infringing synthetic route - Experimentation (Process development, DoE study, optimization and validation). - Purification of Peptide and knowledge of lyophilisation of pure solution. - Handling of analytical HPLC and preparation of buffer. - Characterisation of Peptide using HRMS,2D NMR, IR, Peptide mapping and sequencing. - Preparation of Technology transfer documents. - Scaling-up of process developed at R&D. - Assisting to RA in filing DMF. - General Laboratory Management etc.


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