Associate Scientist

4 days ago

Bangalore Karnataka, India Syngene International Full time

Upstream Process Development Scientist We re looking for an Upstream Process Development Scientist with 2-5 years of experience to join our team In this role you ll be crucial in developing and optimizing upstream processes for the production of large molecules including monoclonal antibodies mAbs and biosimilars If you have a strong background in handling CHO cells and experience with cutting-edge bioreactor systems we encourage you to apply Responsibilities Design execute and analyze experiments for the development and optimization of upstream cell culture processes focusing on CHO cell lines Work with large molecules including monoclonal antibodies mAbs and biosimilars throughout the process development lifecycle Operate and troubleshoot various bioreactor systems including AMBR250 Single-Use Bioreactors SUBs and 10L reactors Optimize cell culture media feeding strategies and process parameters to maximize yield and product quality Analyze process data interpret results and present findings to the team Contribute to the transfer of developed processes to manufacturing Maintain detailed and accurate documentation of all experimental work Stay current with industry trends and advancements in upstream process development Qualifications Master s in Chemical Engineering Biotechnology Bioengineering or a related scientific discipline 2-5 years of hands-on experience in upstream process development within the biopharmaceutical industry Demonstrated expertise in handling and culturing CHO cells Proven experience with large molecule production specifically monoclonal antibodies mAbs and biosimilars Hands-on experience operating and troubleshooting AMBR250 Single-Use Bioreactors SUBs and 10L reactors Strong understanding of cell culture principles bioreactor operations and process scale-up Excellent data analysis troubleshooting and problem-solving skills Ability to work independently and collaboratively in a fast-paced environment Strong written and verbal communication skills Bonus Points if You Have Experience with Design of Experiments DoE software and statistical analysis Knowledge of GMP principles and regulatory guidelines

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