Principle Scientist, Translational Quantitative

6 months ago


Bengaluru Karnataka, India Merck KGaA Full time

Work Your Magic with us

Ready to explore, break barriers, and discover more? We know you've got big plans '“ so do we Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

**Your role**:

- To be able to independently develop quantitative mechanism-based PK/PD models that will inform compound progression decisions from lead optimization to clinical proof of concept and beyond for the immunology and oncology pipelines, both for large and small molecule pharmaceuticals.
- To be able to interact with various project team members in a clear and timely manner, understanding the functions of other team members and being able to explain and educate modeling efforts and results to team members from various backgrounds

Interfaces with other Departments/Functions:

- Oncology and Immunology Research Units
- Clinical Pharmacology (CP)
- Biostatistics
- Safety sciences (Toxicology)
- DMPK
- Epidemiology/Biomarkers
- Pharmacometrics
- Bioinformatics Project Teams (CP, Biomarkers and GPT)

External Interfaces:

- Represent company/ organization in consortia (e.g. IQ working groups) and academic research partnerships.
- Represent function and department in interactions with contractors Present and publish work in relevant journals and MIDD related conferences.

**Who you are**:
EDUCATION/LANGUAGES
- A minimum of 3 years in industry and/or academia in a relevant background
- Fluency in English.

PROFESSIONAL SKILLS & EXPERIENCE
- In-depth hands-on experience with modeling software (such as; MatLab, R, Phoenix/WinNonlin, NONMEM, Monolix etc)
- Experience with DDI predictions using appropriate static and dynamic approaches (SimCyp) are desirable
- Experience with toxicological predictions using tools such as DILI Sym/RenaSym for hepatic and renal toxicity respectively is highly desirable
- Openness to fresh ideas and new perspectives to be gathered from working with people from diverse backgrounds and cultures.
- Flexibility and keen pursuit of innovation throughout all phases of the drug discovery and development process
- A desire to develop and grow by way of taking responsibility and engaging in additional tasks and operations.
- Ability to work independently and deliver results in a timely manner
- Publications in conference proceedings and peer-reviewed journals are encouraged Excellent communication skills with the ability to translate and summarize outcomes of modeling and simulation analysis as relevant for discovery and development projects

Other Requirement:
Normal and routine office duties
Position requires both domestic and international travel up to 20% of time

**What we offer**:We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress


  • Data Scientist

    6 months ago


    Bengaluru, Karnataka, India TE Connectivity Full time

    We are seeking an innovative and technically strong data scientist with background in optimization, machine learning and statistical modelling analysis. You will be part of the Global Supply Chain Analytics team working with global stakeholders, Data Engineers, Network modelers, Visualization experts and Solution Architects to achieve our...


  • Karnataka, India Target Full time

    Join Target as a Principal Data Scientist About Us: Working at Target means helping all families discover the joy of everyday life. We bring that vision to life through our values and culture. Learn more about Target here. As Principal Data Scientist, you will join a Data Sciences team responsible for creating highly personalised offers for our Guests. You...

  • Data Scientist

    4 weeks ago


    Bengaluru, Karnataka, India Moody's Full time

    **Location(s)**: - Quay Building 8th Floor, Bagmane Tech Park, Bengaluru, IN **Line Of Business**: MIS MGMT(MIS MGMT) **Job Category**: - Engineering & Technology **Experience Level**: Experienced Hire At Moody's, we unite the brightest minds to turn today’s risks into tomorrow’s opportunities. We do this by striving to create an inclusive...

  • Data Scientist

    4 weeks ago


    Bengaluru, Karnataka, India NeoStats Full time

    **Job specification**:We are looking for highly talented Data Scientist to join our team in Bengaluru-India**About the Job**: NeoStats is a new age, Data & Analytics firm offering contemporary solutions and infinite possibilities. Our mission is to create a lasting competitive advantage for our clients by transforming them into world-class, data-driven...

  • Data Scientist

    2 months ago


    Bengaluru, Karnataka, India Codex Tech-IT LLC Full time

    Job Location : Bangalore Position Summary The Data Scientist uses machine learning, advanced quantitative analysis, data mining techniques and strong industry acumen to interpret, connect and predict HER data in order to deliver insight and recommendations for clinical and business decisions. The role requires deep familiarity with advanced machine learning...


  • Bengaluru, Karnataka, India Texas Instruments Full time

    **We can't predict what the future holds, but we know Texas Instruments will have a part in shaping it.** Roles and duties: - Stakeholder engagement: - Work collaboratively and strategically with stakeholder groups to achieve TI business strategy and goals - Communicate complex technical concepts and influence final business outcomes with stakeholders...

  • Data Scientist

    6 months ago


    Bengaluru, Karnataka, India Equifax Full time

    As a **Data Scientist **, you will have the opportunity to manipulate large data sets, integrate diverse data sources, data types and data structures into solutions under management guidance. You will build experience developing analytical approaches to meet business requirements, which involves translating requests into use cases, test cases, preparation of...

  • Data Scientist

    2 months ago


    Bengaluru, Karnataka, India NeoStats Full time

    **About the Job**: NeoStats is a new age, Data & Analytics firm offering contemporary solutions and infinite possibilities. Our mission is to create a lasting competitive advantage for our clients by transforming them into world-class, data-driven organizations. Established in 2022 to provide End to End Data & Analytics Services, we are headquartered out of...

  • Data Scientist

    4 months ago


    Bengaluru, Karnataka, India Stellarhire Solutions Full time

    **Basic Qualifications**: - Proficiency in programming languages such as Python, SQL, R etc. - Bachelor or Master's degree in highly quantitative field CS, machine learning,mathematics, statistics) or equivalent experience. - 4-6 years of academic and relevant industry experience. - Proven experience as a Data Scientist with a strong portfolio of data...


  • Karnataka, India Target Full time

    As a Fortune 50 company with more than 400,000 team members worldwide, Target is an iconic brand and one of America's leading retailers. At Target, we have a timeless purpose and a proven strategy. And that hasn’t happened by accident. Some of the best minds from diverse backgrounds come together at Target to redefine retail in an inclusive learning...

  • Data Scientist

    4 weeks ago


    Bengaluru, Karnataka, India Indium Software Full time

    **Job Information**: Date Opened **11/14/2024*** Job Type **Permanent*** RSD NO **9944*** Industry **IT Services*** Min Experience **2*** Max Experience **3*** City **Bangalore North*** State/Province **Karnataka*** Country **India*** Zip/Postal Code **560001*** **Role Title**: Data scientist **Work Experience**: 2-3 years **Educational...


  • Bengaluru, Karnataka, India Google Full time

    **Minimum qualifications**: - Bachelor's degree Statistics, Economics, Mathematics, in a quantitative discipline, or equivalent practical experience. - 5 years of experience in the Industry in a Data Analyst or Data Science role, analyzing data sets to solve business problems through statistical methods and predictive analytics. **Preferred...


  • Bengaluru, Karnataka, India XHire Full time

    **Job Title:** Quantitative AnalystX Hire is seeking a highly skilled Quantitative Analyst to join our analytics team. As a key member of our group, you will play a critical role in developing and implementing quantitative models to drive business growth.**About the Role:**We are looking for an experienced quantitative analyst with a strong background in...

  • Data Scientist

    2 days ago


    Bengaluru, Karnataka, India Lowe's Full time

    Mines and extracts data and applies statistics, machine learning, and deep learning algorithms necessary to derive insights and to develop solutions providing a competitive advantage to the business. - Conducts deep statistical analysis, including predictive and prescriptive modeling, to provide a competitive advantage to the business. - Works with more...


  • Karnataka, India Target Full time

    Principal Data Scientist As a Fortune 50 company with more than 400,000 team members worldwide, Target is an iconic brand and one of America's leading retailers. At Target, we have a timeless purpose and a proven strategy. And that hasn’t happened by accident. Some of the best minds from diverse backgrounds come together at Target to redefine retail in an...

  • Data Scientist

    2 months ago


    Bangalore Urban District, Karnataka, India SymphonyAI Full time

    Introduction: Exciting Opportunity Alert! **Job Description**: As a Data Scientist at Symphony IndustrialAI, you will be ideating and creating solutions for some of the most complex industrial problems utilizing our cutting-edge AI/ML platform. By developing and blending some of the best-in-class AI/ML methods for multivariate time series data, images,...

  • Data Scientist 2

    1 week ago


    Bengaluru, Karnataka, India Bread Financial Full time

    Every career journey is personal. That's why we empower you with the tools and support to create your own success story. Be challenged. Be heard. Be valued. Be you... be here. Job Summary Under supervision and guidance, the Data Scientist, 2 applies data science in advanced analytics such as predictive modeling and data mining in a big data environment in...

  • Data Scientist

    4 months ago


    Bengaluru, Karnataka, India Persistent Systems Full time

    We are seeking an experienced and dynamic Data Scientist to join our team. You will develop ML solutions for customer problems from scratch utilizing large complex data sets of both structured and unstructured formats. Your responsibilities will include developing, prototyping and productionizing ML models. You will have broad expertise in ML techniques...

  • Data Scientist

    6 months ago


    Bengaluru, Karnataka, India PayPal Full time

    At PayPal (NASDAQ: PYPL), we believe that every person has the right to participate fully in the global economy. Our mission is to democratize financial services to ensure that everyone, regardless of background or economic standing, has access to affordable, convenient, and secure products and services to take control of their financial lives. Job...


  • Bengaluru, Karnataka, India Sun Consultants Full time

    Data Scientist Job DescriptionWe are seeking a Quantitative Modeling Expert to join our team at Sun Consultants. The successful candidate will be responsible for applying advanced machine learning algorithms and statistics to drive business growth.The ideal candidate will have 4-7 years of experience in analytics, with a strong background in statistical...