Principal Scientist

2 weeks ago

Hyderabad Telangana, India Novartis Full time

**Summary**:
About the role The Preclinical Safety (PCS) department within the Novartis Biomedical Research Translational Medicine Unit provides world class preclinical safety profiling and assessment for optimal drug discovery, development and commercialization, with state-of-the-art regulatory compliance. As a Preclinical Safety Profiling Expert, you will join our global PCS team to help us to unleash the power of early safety screening and profiling approaches for advancing translational safety assessment and to drive drug discovery and development. You will bring your curious, innovative, and collaborative mindset to leverage a wealth of non-clinical safety-related data generated within our department and deploy state-of-the-art laboratory science and data exploration methods to accelerate the advancement of innovative medicines.

**About the Role**:
Key Responsibilities:

- Design and implement the early safety screening & profiling strategies, including those associated with secondary pharmacology, genetic toxicology and cardiovascular safety, in collaboration with internal and external partners.
- Give to early ADME-Tox data unification, harmonization, curation, and augmentation to support the Predictive Safety Strategy
- Effectively communicate with customers, including experimental design, data quality, timeline requirements and flowchart planning.
- Understand and implement agreed business strategy defined by local and global Preclinical Safety Profiling requirements, help to lead budget, ensuring appropriate coordination of projects.
- Participate in cross-functional early safety screening & profiling collaborations with Novartis Biomedical Research partners to support the early derisking of compounds, drug targets, and therapeutic modalities
- Deliver clear and concise presentations for audiences with different expertise
- In collaboration with cross-functional partners, provide scientific and strategic input to support the early derisking of compounds, drug targets, and therapeutic modalities
- Ensure quality and compliance of data generation, analyses and resultant reports

Essential Requirements:

- PhD with 2+ years or MVSc/MS/M.Pharm with 6+ years of relevant work experience in pharmacology / toxicology
- Understands the basic concepts of hazard identification and risk assessment associated with drug ADME, off-target mitigation, genetic toxicology, and cardiovascular safety.
- Familiar with early drug discovery processes
- Experience with data integrity and quality assurance practices.
- Excellent communication skills and ability to translate analytical concepts for diverse audience and collaborators (English is our primary language

Desirable Requirement:

- Articulates solutions /recommendations to business users. Presents analytical content concisely and effectively to non-technical team members and influences the outcome of predictive safety profiling contributions.
- Coordinates, prioritizes and efficiently allocates resources to critical initiatives: plans resources proactively, anticipates and actively manages change, sets stakeholder expectations as required, identifies operational risks and enable the team to drive issues to resolution, balances multiple priorities and minimizes surprise blocking issues.
- Collaborates with internal stakeholders, external partners, and cross-functional teams to solve critical business problems, propose operational efficiencies and innovative approaches.
- Familiar with visualization tools to increase efficiency and quality of the data communication and interpretation.
- Team player
- Strives for continuous learning (scientific and technical).

Commitment to Diversity & Inclusion:

- We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our

Commitment to Diversity and Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

Division

Biomedical Research

Business Unit

Pharma Research

Location

India

Site

Hyderabad (Office)

Company / Legal Entity

IN10 (FCRS = IN010) Novartis Healthcare Private Limited

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No

Novartis is committed to building an outstanding, inclusive work environment and diverse teams' representative of the patients and communities we serve.

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