Scientist Iii, Protein Biology

7 months ago

Bengaluru Karnataka, India Thermo Fisher Scientific Full time

Job Description**Job Title: ScientistIII, Protein Biology**

**Job Location: India, Bangalore**

**About Company**:
**About the company**

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our Innovative Laboratory technologies & Services makes it easier for customers.

**About Team: Antibody team**

**Role & Responsibilities**

**To play a crucial role within an antibody development team, spearheading the advancement of phage display-based antibody development through the implementation of cutting-edge molecular, protein, and cell biology techniques.**

**Responsibilities**:
**Experimental Design and Execution**: Develop and implement experimental strategies for phage display projects, including library construction, selection, and screening. Design and optimize appropriate assays for protein binding or activity measurements.**Library Construction**: Generate diverse and high-quality phage display libraries by cloning target genes into phage vectors. Ensure library diversity and size meet project requirements.**Selection and Screening**: Perform phage display selections to isolate specific binding or functional interactions. Develop and execute appropriate screening protocols, including affinity-based selections or functional assays.**Molecular Biology Techniques**: Proficiently perform molecular biology techniques such as PCR, DNA cloning, protein expression, and purification. Ensure quality control measures are implemented to validate constructs and protein production.-
**Data Analysis and Interpretation**: Analyze and interpret experimental data generated from phage display experiments. Use statistical methods and bioinformatics tools to identify binding or functional motifs, analyze sequence-activity relationships, and propose protein engineering strategies.**Collaboration and Communication**: Collaborate with multidisciplinary teams, including scientists from biology, chemistry, and bioinformatics, to drive project success. Clearly communicate research findings, progress, and recommendations through oral presentations and written reports.**Equipment and Lab Management**: Maintain and operate laboratory equipment required for phage display experiments. Ensure compliance with safety guidelines, maintain accurate records, and manage inventory and ordering of necessary reagents and supplies.-
**Troubleshooting and Problem Solving**:Identify and troubleshoot technical issues that arise during phage display experiments. Develop innovative solutions to overcome challenges and optimize experimental protocols.**Education & Experience levels**:
Applicants should have Masters with greater than 5 years relevant experience or PhD with greater than 2 years’ experience in a life sciences field with a strong focus on structural biology, protein design, protein purification, molecular biology, immunology, biotechnology or biochemistry and experience with display based antibody development technologies

**Nature of experience**:

- Proficiency in display-based antibody development techniques, demonstrating a strong track record of successful projects.
- In-depth knowledge of display platforms such as phage display, yeast display, or bacterial display.
- Experience in antibody library construction, screening, and optimization using display-based methods.
- Familiarity with antibody engineering and optimization strategies, including affinity maturation and humanization.
- Proficient in molecular biology techniques, including DNA manipulation, cloning, and protein expression.
- Strong analytical and problem-solving skills, with the ability to troubleshoot and optimize display-based antibody development protocols.
- Excellent communication and collaboration skills to work effectively in cross-functional teams.
- Attention to detail and ability to meticulously analyze and interpret experimental data.
- Flexibility and adaptability to work in a fast-paced research environment.

Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics,

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