Principal scientist

1 week ago

Hyderabad, India CDC Global Solutions Full time

We are retained with one of the fastest-growing Contract Research, Development, and Manufacturing Organizations (CRDMOs). As a pure-play, full-service partner, they collaborate with over 300 global innovative pharma and biotech companies to accelerate the discovery, development, and commercialization of their NCE programs. They have over 3000 employees across our facilities in India, the UK, and the USA, working together to deliver scientific excellence and customer success. They are also established as a Great Place to Work certified organization with a culture of openness, mutual respect, and inclusivity. We are seeking talent from Europe or the US who want to; ✓ Relocate to Hyderabad, India. ✓ Have a Ph. D. and / or Post Doc from a reputed global university. Career Opportunities for Global Scientific Talent for Biology, DMPK verticals. 1) Bioanalysis - Deep understanding and expertise in developing and troubleshooting complex bioanalytical methods using LC-HR-MS, ELISA and MSD. Demonstrated experience in Bioanalytical capabilities to support new modalities- Peptides, Antibody drug conjugates, ASOs. 2) In vitro ADME - Experience in conducting in In vitro ADME assays to characterise Peptides, Antibody drugconjugates, ASOs. Deep understanding and expertise in cell biology, cell permeability hepatocytes, 3 D cultures, image analysis, drug transporters and enzymology. Interpersonal skills and strong communication skills in English. Ability to collaborate with cross functional teams and design the strategies to support discovery programs and meeting the goals of discovery projects on time. 3) PK/PD and modelling and Simulations - Experience in building the PK/PD models using Pheonix Win Nonlin, R, Monolix, NONMEM, MATLAB or any other custom built software. Holistic drug discovery experience in understanding the PK/PD, exposure-response modeling with Small molecules, ADC and other new modalities. Design PK/PD strategies and develop models to predict the doses in the animal models and prediction of FIH doing using complex disease models. We will fully support any relocation costs for family members

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