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Associate Scientist
3 months ago
Designation: Associate Scientist
Job Location: Bangalore
About Syngene:
At Syngene, safety is at the heart of everything we do personally and professionally. Syngene has placed safety at par with business performance with shared responsibility and accountability, including following safety guidelines, procedures and SOPs, in letter and spirit.
The mandatory expectation for all roles as per Syngene safety guidelines:
Overall adherence to safe practices and procedures of oneself and the teams aligned Contributing to the development of procedures, practices and systems that ensures safe operations and compliance to companys integrity & quality standards Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times. Ensuring safety of self, teams, and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace. Ensure all assigned mandatory training related to data integrity, health, and safety measures are completed on time by all members of the team including self Compliance with Syngene's quality standards at all times.Job Purpose:
A highly motivated individual with a strong interest in Bioanalytical and in-vitro ADME assays is required for our current replacement. In this position, the candidate will support compound screening efforts in standard in-vitro ADME assays and bioanalysis.
Key Responsibilities:
Perform in vitro ADME assays such as solubility, metabolic stability, CYP450 inhibition, CYP induction, plasma protein binding, TDI, etc Perform in vitro cell-based assays like - hPXR, Caco-2 Permeability assay Processing of plasma and tissue samples for bioanalysis Perform timely bioanalysis of In vitro ADME samples using LC-MS/MS Independently able to develop a robust bioanalytical method and application of quantitative methods for ADME studies Operating instruments like LC-MS/MS for compound tuning and analysis, followed by data retrieval, method development of NCEs in plasma and other matrices Understand and interpret ADME data Analytical problem-solving skills.Syngene Values:
All employees will consistently demonstrate alignment with our core values.
Excellence Integrity ProfessionalismEducational Qualification: M.Sc (Chemistry/Biological Sciences)/M. Pharm from a reputed University
Work Experience: 3 to 6 years of experience in industry.
Technical/Functional Skills:
Prior experience in handling NCEs, analysis by LC-MS/MS, sample processing Prior experience in standard in vitro ADME assays.Behavioral/Managerial Skills:
High interpersonal skills, and excellent oral & written communication skills. Problem-solving, time-management skills, multi-tasking.Equal Opportunity Employer:
It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.
