Team Member/Manager

3 weeks ago

New Delhi, India Cipla Full time

JDRole is to take the lead and conduct device development for Meter Dose Inhaler dosage form. Primary role is to co-ordinate with device manufacturers for selecting the right device and responsible for conduiting design verification to comply the defined user requirements. The candidate will be responsible for test method /fixtures development, relevant testing, validation, In-silico clinical simulations that relate to patient safety, efficacy and clinical outcomes. Commercial product support for MDI portfolio.Additionally, candidate will be responsible for new product development for Injectable delivery devices – including technology / device platform selection, design fine tuning and development .Should have basic knowledge in medical devices, CFD & other simulation tools. Degree in engineering with ~12 years experience in medical device characterization mandatory.Device DevelopmentLead device workstream for Metered Dose Inhaler Dosage form, from device selection, development, troubleshooting to regulatory submissions and commercial support.Support development of injectable drug-device combination products. Custom design / design troubleshooting of delivery devices.Build in-vitro setups, test various design iterations, analysis drug delivery performanceLab experiment to validate simulation resultsMechanical Force testing expertise, Ability to design fixtures and test methodsfamiliarity with aerosol testing methodologiesDrug deposition modelling and predictions, Famility with CFD, FEA tools.CFD interpretation from modelling dataBuild models in MATLAB and interpret the resultsDesign history and clinical simulation documentationBuild protocols for patient specific device or robustness and compile information as per latest regulatory guidance and thinkingBuild Design History File (DHF) per Design Controls, SupportDocumentation for combination productsReference product characterizationPreparation of specifications, trade dress, different stage gate document.Threshold AnalysesDevice design history file /Design Controls for combination productsCapable to design the user requirements for combination products.Work with device manufacturer & Formulation team for completion of successful design verification, in compliance with various ISO /FDA requirements.Conduct Design validation (HF/Threshold Analysis).Work with formulation or different stake holder to complete device documentation such as functional specifications, quality attributes.Derive and user risk mitigation for combination product.Educational qualifications:Engineering degree BE/BTech(Mechanical preferable)Relevant experience:Experience at reputed of around 12 years in medical device development or drug delivery devices in pharmaceutical industryKnowledge in medical devices / combination product developmentKnowledge in authoring Design History fileTest Method development & validationKnowledge on Primary container closures system and regulatory expectations

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