Specialist - Bioanalysis (In Vitro DMPK)

17 hours ago

New Delhi, India Aurigene Pharmaceutical Services Limited Full time

Role : Specialist - Bioanalysis (In Vitro DMPK)Job Location : BengaluruAs a Specialist, you will be the technical expert for all in vitro bioanalytical activities, ensuring the accurate, timely, and efficient delivery of ADME data to support drug discovery and development projects.Key Responsibilities:- LC-MS/MS Mastery: Serve as the subject matter expert for the operation, maintenance, and advanced troubleshooting of LC-MS/MS instruments used for ADME sample analysis. - Bioanalytical Execution: Plan, execute, and analyze a diverse range of in vitro ADME Assays, including: - Permeability Studies: Cell-based models (e.g., Caco-2, MDCK) and non-cell-based assays (PAMPA). - Metabolic Stability: Assays such as Hepatocyte and Microsomal stability, and CYP-Inhibition. - Physicochemical & Stability: High-throughput solubility, Plasma, Buffer, SGF, and SIF stability assessments. - Project Flow Optimization: Maintain and optimize the bioanalytical project workflow to ensure efficient throughput and meet all study timelines. - Physicochemical Profiling: Lead the execution of Kinetic solubility, Thermodynamic solubility, and Chromatographic Log D studies. - Metabolite Identification (MET-ID): Analyze MET-ID samples and prepare detailed, comprehensive reports. - Team Leadership: Act as a mentor, providing hands-on training and technical guidance to junior team members on various bioanalytical techniques and protocols.Qualifications & Experience:- Qualification: M. Pharma - Experience: 8 to 15 years of direct, relevant experience in bioanalysis, with a strong focus on DMPK/ADME studies, preferably within a pharmaceutical or CRO setting. - Technical Skills: Must be highly proficient and well-versed in handling and executing bioanalytical assays using LC-MS/MS technology.Ready to Apply?If your profile aligns with this challenging and rewarding role, please share your CV with:krishnafulsure@aurigeneservices.com Subject Line: Bioanalysis – Invitro DMPK

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