Research Scientist/Team Leader – Biocatalysis, Protein purification

1 week ago


New Delhi, India PI Industries Ltd Full time

Key Responsibilities:- Design and execute experiments for enzyme screening, expression, and purification (affinity, ion exchange, HIC, SEC, etc.). - Design studies and lead workstreams for lab‑to‑kilo scale (biotransformations 0.1–20 L; purification mg–10 g and higher) - Drive process robustness/scale‑up, troubleshoot enzyme stability/mass transfer/fouling/resin lifetime. - Characterize enzymes using biochemical and biophysical techniques (SDS-PAGE, HPLC, LC-MS, UV-Vis, etc.). - Collaborate with molecular biology, fermentation, and analytical teams to ensure seamless workflow. - Maintain accurate records, analyse data, and present findings in internal meetings. - For TL/SRS roles: Lead project teams, coordinate cross-functional activities, and contribute to strategic planning.What You Bring:Qualification: M.Sc./M.Tech. /Ph.D. (Ph.D. is preferred for SRS/TL) in Biochemistry, Biotechnology, Chemical/Bioprocess Engineering with excellent academic credentials, and peer-reviewed papers/ patentsExperience:- RS: 3–5 yrs. (M.Sc.) or fresh Ph.D. - SRS: 5–8 yrs. (M.Sc.) or 2–4 yrs. (Ph.D.) - TL: 8–12 yrs. (M.Sc.) or 5–8 yrs. (Ph.D.) with ≥2 yrs. team leadership. - Biocatalysis: Enzyme selection/screening, cofactor recycling, immobilization basics, solvent/aqueous systems, pH/DO/mass transfer control, scale‑up, green metrics - Purification/ Downstream (from industry): Clarification, precipitation, AKTA/FPLC, chromatography (Affinity/IEX/HIC/SEC), UF/DF/TFF, solvent exchange, crystallization/lyophilization. - Analytics/Tools: HPLC/UPLC, GC, LC‑MS, SDS‑PAGE, chiral analytics, DoE (JMP/Minitab), ELN/LIMS, strong Excel/data handling.Functional Competencies: Scientific knowledge, Experimental skills, Documentation, Data reporting, analysis and interpretationBehavioural Competencies: Drive for result, Clear communication, Safety/process adherence, Ability to work independently and in a team-oriented environment.Interested Candidates are requested to share their resumes on shubhi.chandnani@piind.com



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