Downstream Purification

4 weeks ago


Bengaluru, India Biocon Biologics Full time

At Biocon Biologics, we are creating a model for the future of healthcare for all. We are a leading company in the biosimilars revolution where patients come first. Our ambition is to impact a billion lives and we do this by fostering a culture of affordable innovation, patient centricity and disruptive thinking. We are a multicultural global company where employees have a purpose and passion to work closely with partners and patients. We have proven end to end expertise in the field of biosimilars, from its development, manufacturing, clinical development, regulatory approvals to commercialization. We have a long-term commitment to bring high quality affordable biosimilars to patients all over the globe.



About the Role :


  • Individually contributing to the design, execution, analysis, documentation and archival of complex experiments related to downstream process development of biologics at lab, pilot and manufacturing scale.
  • Supporting technology transfer from R&D to pilot plant and manufacturing.
  • Participating actively in cross-functional meetings and communicate key findings.
  • Participating actively in key regulatory filings.
  • Supporting process characterization and validation of biologics.
  • Maintaining a safe workplace by adhering to prevalent EHS and OSHA standards.
  • Collaborate with QA, QC, Manufacturing and Regulatory functions in order to successfully deliver drugs to customers.
  • Contributing to project planning, logistics.
  • Providing support to other team members as per priority and requirement.
  • Perform literature reviews and summarize relevant topics for the development of work streams.


Requirements:


  • A successful candidate for this position will display many of the following attributes:
  • Minimum of M.Tech/M.S in Chemical Engineering/Biotechnology/Biochemistry/Biochemical Engineering and other related fields a must.
  • Knowledge of downstream process development, product purification, protein biochemistry, separation processes: filtration, TFF, Chromatography, extraction, enzymatic reactions, crystallization, lyophilization etc. and their underlying theory.
  • Hands-On Experience in handling the following equipment: GE AKTA Chromatography Systems, TFF Equipment, Centrifuge, Filtration systems, HPLCs.
  • Understands statistics and can perform data analysis. Enthusiastic to build on their statistical skills.
  • Passionate about developing scalable processes
  • Adaptable to work in an agile, fast paced environment with competing priorities, evolving goals.
  • Able to work within a team and complement strengths of other team members
  • Experience with Empower CDS a plus
  • Able to work independently, possess excellent communication skill, problem-solving skills.
  • Able to work with cross-functional teams successfully and communicate technical findings.


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